Endocrine Abstracts

CFTR modulators are drugs that enhance/restore the expression, function, or stabilize the defective CFTR protein in patients with cystic fibrosis (CF). These modulators have shown marked improvements in lung function and quality of life for people with CF but their role in glucose tolerance is still unclear1. At Nottingham Children’s Hospital, children with CF are eligible for kaftrio treatment (Elexacaftor/tezacaftor/ivacaftor CFTR modulator) from 10 years of ...